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5-hydroxymethyl-2-furaldehyde
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
5-hydroxymethyl-2-furaldehyde图片
CAS NO:67-47-0
包装:20mg
市场价:777元

产品介绍
源自山茱萸的 5-hydroxymethyl-2-furaldehyde (2-Hydroxymethyl-5-furfural) 作为压力源抑制酵母生长和发酵。
Cas No.67-47-0
别名5-羟甲基糠醛; 2-Hydroxymethyl-5-furfural; 2-Formyl-5-hydroxymethylfuran
化学名5-(hydroxymethyl)furan-2-carbaldehyde
Canonical SMILESC1=C(OC(=C1)C=O)CO
分子式C6H6O3
分子量126.11
溶解度DMF: 1mg/mL,DMSO: 3mg/mL,Ethanol: 2.5mg/mL,PBS (pH 7.2): 10mg/mL
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

5-Hydroxymethylfurfural (2-Hydroxymethyl-5-furfural), derived from lignocellulosic biomass, inhibits yeast growth and fermentation as stressors.

It is found that furfural and HMF cause the attenuation of bulk translation activity and the assembly of cytoplasmic mRNP granules in Saccharomyces cerevisiae. Notably, a combination of furfural and HMF induce the remarkable repression of translation initiation and SG formation. Furfural and HMF can induce the formation of cytoplasmic mRNP granules, HMF also causes a gradual reduction in the polysome fraction and a concomitant increase in the 80S monosome fraction[1].

References:
[1]. Iwaki A, et al. Biomass conversion inhibitors furfural and 5-hydroxymethylfurfural induce formation of messenger RNP granules and attenuate translation activity in Saccharomyces cerevisiae. Appl Environ Microbiol. 2013 Mar;79(5):1661-7.