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Destruxin A
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Destruxin A图片
CAS NO:6686-70-0
包装:1mg
市场价:7650元

产品介绍
Destruxin A (DA) 是一种来自昆虫病原真菌绿僵菌的环肽真菌毒素,具有杀虫、抗病毒和抗增殖活性。
Cas No.6686-70-0
别名绿僵菌素A,SB 242533
化学名cyclo[N-methyl-L-alanyl-β-alanyl-(2R)-2-hydroxy-4-pentenoyl-L-prolyl-L-isoleucyl-N-methyl-L-valyl]
Canonical SMILESO=C(N[C@]([C@@H](C)CC)([H])C(N(C)[C@@H](C(C)C)C(N(C)[C@H]1C)=O)=O)[C@@]2([H])N(CCC2)C([C@@H](CC=C)OC(CCNC1=O)=O)=O
分子式C29H47N5O7
分子量577.7
溶解度Acetonitrile: Soluble,DMF: Soluble,DMSO: Soluble
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Destruxin A is a cyclic hexadepsipeptide mycotoxin first isolated fromO. destructorand commonly found in entomopathogenic fungi.1It has insecticidal activity by affecting diverse pathways, including those related to immune response, calcium signaling, and development.2,3

References:

1. Pedras, M., Zaharia, L.I., and Ward, D.E. The destruxins: Synthesis, biosynthesis, biotransformation, and biological activity Phytochemistry 59(6), 579-596 (2002).
2. Han, P., Jin, F., Dong, X., et al. Transcript and protein profiling analysis of the Destruxin A-induced response in larvae of Plutella xylostella PLoS One 8(4), (2013).
3. Pal, S., St.Leger, R.J., and Wu, L.P. Fungal peptide Destruxin A plays a specific role in suppressing the innate immune response in Drosophila melanogaster J.Biol.Chem. 282(12), 8969-8977 (2007).