CAS NO: | 2375846-41-4 |
包装 | 价格(元) |
5mg | 电议 |
10mg | 电议 |
25mg | 电议 |
50mg | 电议 |
100mg | 电议 |
Cas No. | 2375846-41-4 |
分子式 | C25H28F2N2O4 |
分子量 | 458.5 |
溶解度 | DMSO : 100 mg/mL (218.10 mM; ultrasonic and warming and heat to 60°C) |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | IC50: 0.60 μM (rat TrxR1)[1] DVD-445 (Compound 7) is a potent peptidomimetic covalentthioredoxin reductase 1 (TrxR1)inhibitor with anIC50of 0.60 μM for rat TrxR1. DVD-445 has good anticancer application[1]. DVD-445 (Compound 7) shows a cytotoxic effect in SH-SY5Y, U87, HaCaT cell lines and PBMCs withIC50s of 10.99 μM, 9.70 μM, 8.30 μM, 55.71 μM, respectively[1]. |