CAS NO: | 568-01-4 |
包装 | 价格(元) |
1mg | 电议 |
5mg | 电议 |
Cas No. | 568-01-4 |
Canonical SMILES | O=C1C2=C(N(C)C3=C4OCOC4=C(C(OC)=C13)OC)C=CC=C2 |
分子式 | C17H15NO5 |
分子量 | 313.3 |
储存条件 | -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Melicopine is an acridone alkaloid that has been found inZ. simulansand has antimalarial and anticancer activities.1It is active against the chloroquine-sensitive 3D7 and chloroquine-resistant Dd2 strains ofP. falciparumwith IC50values of 29.7 and 33.7 µg/ml, respectively. Melicopine is cytotoxic to PC-3M and LNCaP prostate cancer, but not non-cancerous HEK293, cells (IC50s = 47.9, 37.8, and >100 µg/ml, respectively). 1.Wang, C., Wan, J., Mei, Z., et al.Acridone alkaloids with cytotoxic and antimalarial activities from Zanthoxylum simullans HancePharmacogn. Mag.10(37)73-76(2014) |