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NAG-thiazoline
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
NAG-thiazoline图片
CAS NO:179030-22-9
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议

产品介绍
An OGA inhibitor
Cas No.179030-22-9
别名N-乙酰-葡糖胺基噻唑啉
Canonical SMILESO[C@@H]1[C@]2([H])[C@](SC(C)=N2)([H])O[C@@H]([C@H]1O)CO
分子式C8H13NO4S
分子量219.3
溶解度DMF: 30 mg/ml,DMSO: 25 mg/ml,Ethanol: 30 mg/ml,PBS (pH 7.2): 5 mg/ml
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

NAG-thiazoline is an inhibitor of O-GlcNAcase (OGA; Ki= 180 nM).1It is active againstV. campbellii(MIC = 0.5 µM).2

1.Macauley, M.S., and Vocadlo, D.J.Increasing O-GlcNAc levels: An overview of small-molecule inhibitors of O-GlcNAcaseBiochim. Biophys. Acta1800(2)107-121(2010) 2.Meekrathok, P., Stubbs, K.A., Aunkham, A., et al.NAG-thiazoline is a potent inhibitor of the Vibrio campbellii GH20 β-N-AcetylglucosaminidaseFEBS J.287(22)4982-4995(2020)