您好,欢迎来到试剂信息网! [登录] [免费注册]
试剂信息网
位置:首页 > 产品库 > AZ6102
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
AZ6102
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
AZ6102图片
CAS NO:1645286-75-4
包装与价格:
包装价格(元)
10mg电议
25mg电议
50mg电议

产品名称
AZ-6102, AZ 6102
产品介绍

生物活性

AZ6102是有效的TNKS1/2抑制剂,对其他PARP家族酶具有100倍的选择性,对DLD-1细胞中Wnt途径的抑制作用的IC50为5 nM。

靶点信息

TNKS1TNKS2

化学数据

目录号A15873
作用机制Inhibitor (抑制剂)
M. Wt428.53
FormulaC25H28N6O
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.1645286-75-4
SynonymsAZ-6102, AZ 6102
SMILESC[C@H]1CN(C2=NC=C(C3=CC=C(C4=NC(C(C=CN5C)=C5N4)=O)C=C3)C(C)=C2)C[C@@H](C)N1

溶解度

In vitroDMSO83 mg/mL (193.68 mM)
WaterInsoluble
EthanolInsoluble
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM23.34 mL116.68 mL233.36 mL
0.5 mM4.67 mL23.34 mL46.67 mL
1 mM2.33 mL11.67 mL23.34 mL
5 mM0.47 mL2.33 mL4.67 mL

*The above data is based on the productmolecular weight 428.53. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.