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Arbutamine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Arbutamine图片
CAS NO:128470-16-6
包装:1mg
市场价:6750元

产品介绍
Arbutamine是一种短效的,非选择性β-肾上腺素受体(β-adrenoceptor)激动剂,可增加心率,心脏收缩力和收缩压。Arbutamine是一种用于儿科心脏应激因子的儿茶酚胺。
Cas No.128470-16-6
别名(R)-4-[1-羟基-2-[[4-(4-羟基苯基)丁基]氨基]乙基]-1,2-苯二醇
Canonical SMILESOC1=CC=C([C@@H](O)CNCCCCC2=CC=C(O)C=C2)C=C1O
分子式C18H23NO4
分子量317.38
储存条件Store at -20°C, protect from light, stored under nitrogen
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Arbutamine is a short-acting, potent and nonselective β-adrenoceptor agonist that increases heart rate, cardiac contractility, and systolic blood pressure[1]. Arbutamine is a catecholamine for a pharmacological cardiac stress agen[2].

Arbutamine (i.v.; 5, 10, 50, 100, and 250 ng/kg/min) increases mean heart rate, peak positive left ventricular pressure and its first time-derivative, and normal-zone myocardial thickening in 8 open-chest dogs (mean weight, 26.91 kg).

[1]. Ruiz M, et al. Arbutamine stress perfusion imaging in dogs with critical coronary artery stenoses: (99m)Tc-sestamibi versus (201)Tl. J Nucl Med. 2002 May;43(5):664-70. [2]. Nagarajan R, et al. A novel catecholamine, arbutamine, for a pharmacological cardiac stress agent. Cardiovasc Drugs Ther. 1996 Mar;10(1):31-8.