Cas No. | 799268-65-8 |
别名 | D-(+)-SN-1-O-花生四烯-甘油基-3-磷酸 |
Canonical SMILES | O[C@@H](COP([O-])(O)=O)COC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O.[NH4+] |
分子式 | C23H38O7P•NH4 |
分子量 | 475.6 |
溶解度 | Methanol: sparingly soluble |
储存条件 | Store at -80°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | 1-Arachidonoyl lysophosphatidic acid is a phospholipid containing arachidonic acid at the sn-1 position. It has been found in rat brain as 37% of the arachidonic acid-containing lysophosphatidic acid (LPA) species and is a precursor to 1-arachidonoyl glycerol . 1-Arachidonoyl lysophosphatidic acid binds to the LPA2/EDG4 receptor with an EC50 value of approximately 10 nM. It prevents TNF-α and IL-6 secretion in wild-type but not Lpa2-/- dendritic cells stimulated by LPS. It also decreases differentiation of HT-29 human colon carcinoma cells to goblet cells in the presence of sodium butyrate. |