(R)-(-)-Mellein 是一种从这种曲霉的培养液中分离出来的抗生素。
Cas No. | 480-33-1 |
别名 | (R)-蜂蜜曲菌素,以及(S)-蜂蜜曲菌素,(R)-Mellein |
Canonical SMILES | CC(O1)CC2=C(C(O)=CC=C2)C1=O |
分子式 | C10H10O3 |
分子量 | 178.2 |
溶解度 | DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml,Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | (R)-(-)-Mellein is a dihydroisocoumarin compound produced by A. ochraceus Wilhelm. It has a variety of biological activities including antibacterial, antimalarial, antifungal, and anticancer effects. (R)-(-)-Mellein inhibits proliferation of human breast cancer (MCF-7 and MDA-MB-468) and melanoma (SK-MEL-28 and Malme-3M) cell lines with IC50 values greater than 200 μM. |