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ML-098
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
ML-098图片
CAS NO:878978-76-8
包装与价格：
包装价格(元)
5mg电议
10mg电议
25mg电议

产品介绍
ML-098 (CID-7345532) 是 GTP 结合蛋白 Rab7 的激活剂，EC50 为 77.6 nM。
Cas No.878978-76-8
别名CID-7345532
化学名1-[2-(2,5-dimethylphenoxy)ethyl]-1H-indole-3-carboxylic acid
Canonical SMILESCC1=CC=C(C)C(OCCN2C(C=CC=C3)=C3C(C(O)=O)=C2)=C1
分子式C19H19NO3
分子量309.4
溶解度≤5mg/ml in DMSO
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

ML-098 (CID-7345532) is an activator of the GTP-binding protein Rab7 with an EC50 of 77.6 nM.

Probe compound mL098 (CID-7345532) functions by increasing the affinity of the GTPases for guanine nucleotides, leading to the hypothesis that these activators interact with GTPases bind to an allosteric binding site localized between switch regions I and II. ML-098 is an activator of the GTP-binding protein Rab7 with an EC50 of 77.6 nM which shows selectivity against the related GTPases cdc42, Ras, Rab-2A, and Rac1 (EC50s = 588.8, 346.7, 158.5, and 794.3 nM, respectively)[1].