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17α,20β-Dihydroxy-4-pregnen-3-one
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
17α,20β-Dihydroxy-4-pregnen-3-one图片
CAS NO:1662-06-2
包装与价格：
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍
An endogenous, maturation-inducing steroid
Cas No.1662-06-2
别名4-孕烷-17Α,20Β-二醇-3-酮,17α,20β-DHP，17α,20β-dihydroxy Progesterone
化学名17,20R-dihydroxy-pregn-4-en-3-one
Canonical SMILESC[C@@H](O)[C@@]1(O)CC[C@@]2([H])[C@]3([H])CCC4=CC(CC[C@]4(C)[C@@]3([H])CC[C@@]21C)=O
分子式C21H32O3
分子量332.5
溶解度1mg/mL in ethanol, 1mg/mL in methanol, 1mg/mL in acetonitrile
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

17α,20β-Dihydroxy-4-pregnen-3-one (17α,20β-DHP) is an endogenous, maturation-inducing steroid that stimulates oocyte maturation in females of several teleost species. For example, 1 μg/ml of 17α,20β-DHP applied to Persian sturgeon oocytes has been shown to effectively induce germinal vesicle breakdown, an essential step during oocyte maturation.1 Gonadotropin-releasing hormone and the gonadotropins, follicle-stimulating hormone and luteinizing hormone, have been shown to stimulate the production of 17α,20β-DHP either in vivo or in vitro.[2] 17α,20β-DHP has also been reported to influence spermiation by stimulating milt production when administered at 5 mg/kg to various male teleosts.[1]

Reference:
[1]. Milla, S., Terrien, X., Sturm, A., et al. Plasma 11-deoxycorticosterone (DOC) and mineralocorticoid receptor testicular expression during rainbow trout Oncorhynchus mykiss spermiation: Implication with 17alpha, 2βdihydroxyprogesterone on the milt fluidity? Reproductive Biology and Endocrinology 6, 19 (2008).
[2]. Planas, J.V., and Swanson, P. Maturation-associated changes in the response of the salmon testis to the steroidogenic actions of gonadotropins (GTH I and GTH II) in vitro. Biology of Reproduction 52(3), 697-704 (1995).