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m-PEG8-Tos
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
m-PEG8-Tos图片
CAS NO:82217-01-4
包装:1g
市场价:8146元

产品介绍
Tos-PEG8-m 是水飞蓟宾醚的衍生物,来源于专利 CN105037337A (化合物 III-d)。Tos-PEG8-m 是基于 PEG 的 PROTAC 接头,可用于合成水飞蓟素。
Cas No.82217-01-4
分子式C24H42O11S
分子量538.65
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Tos-PEG8-m is a derivative of silybin ethers, extracted from patent CN105037337A (compound III-d). Tos-PEG8-m is a PEG-basedPROTAC linkercan be used in the synthesis of Silymarin[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.
PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

[1]. Yuxia Zhao, et al. Derivative of silybin ethers, and synthetic method and application thereof. Patent CN105037337A.