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7-Epitaxol
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
7-Epitaxol图片
CAS NO:105454-04-4
包装:20mg
市场价:1386元

产品介绍
7-Epitaxol 是紫杉醇的一种活性代谢物，其抗细胞复制、促进微管束形成和抗微管解聚的活性与紫杉醇相当。
Cas No.105454-04-4
别名7-表紫杉醇; 7-epi-Paclitaxel
Canonical SMILESCC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)C6=CC=CC=C6)O)O)OC(=O)C7=CC=CC=C7)(CO4)OC(=O)C)O)C)OC(=O)C
分子式C47H51NO14
分子量853.91
溶解度≥ 85.4mg/mL in DMSO
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

7-epi-Taxol is an active metabolite of taxol, with activity comparable to that of taxol against cell replication, promoting microtubule bundle formation and against microtubule depolymerization.

7-epi-Taxol (7-Epitaxol) is a metabolite of taxol[1]. 7-epi-Taxol has activity comparable to that of taxol on cell replication, microtubule bundle formation and in vitro microtubule polymerization[2].

References:
[1]. Royer I, et al. Paclitaxel metabolites in human plasma and urine: identification of 6 alpha-hydroxytaxol, 7-epitaxol and taxol hydrolysis products using liquid chromatography/atmospheric-pressure chemical ionization mass spectrometry. Rapid Commun Mass Spectrom. 1995;9(6):495-502.
[2]. Ringel I, et al. Taxol is converted to 7-epitaxol, a biologically active isomer, in cell culture medium. J Pharmacol Exp Ther. 1987 Aug;242(2):692-8.