| CAS NO: | 480-44-4 |
| 包装 | 价格(元) |
| 10mM (in 1mL DMSO) | 电议 |
| 20mg | 电议 |
| Cas No. | 480-44-4 |
| 别名 | 金合欢素; 5,7-Dihydroxy-4'-methoxyflavone |
| 化学名 | 5,7-dihydroxy-2-(4-methoxyphenyl)chromen-4-one |
| Canonical SMILES | COC1=CC=C(C=C1)C2=CC(=O)C3=C(C=C(C=C3O2)O)O |
| 分子式 | C16H12O5 |
| 分子量 | 284.26 |
| 溶解度 | ≥ 10.65mg/mL in DMSO |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Acacetin (5,7-Dihydroxy-4'-methoxyflavone) was a 4.0-fold and 5.5-fold more potent inhibitor of BACE-1 than oleanolic acid and maslinic acid, respectively.Acacetin (5,7-Dihydroxy-4'-methoxyflavone) significantly suppressed the photoreceptor collapse. Acacetin (5,7-Dihydroxy-4'-methoxyflavone) significantly reduces the Aβ levels by interfering with human APP proteolytic processing and BACE-1 expression. Acacetin (5,7-Dihydroxy-4'-methoxyflavone) inhibited the generation of the APP-CTF by affecting APP cleavage. Acacetin (5,7-Dihydroxy-4'-methoxyflavone) prolongs lifespan of significantly in the dose dependent manner[1]. References: |
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