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Flavokawain A
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Flavokawain A图片
CAS NO:3420-72-2
包装与价格：
包装价格(元)
10mM (in 1mL DMSO)电议
50mg电议

产品介绍
FlavokawainA是一种抗癌试剂(anticarcinogenicagent)，是kava提取物中的查耳酮，具有抗肿瘤活性。FlavokawainA通过Bax蛋白依赖和线粒体依赖的凋亡途径诱导细胞凋亡(apoptosis)。FlavokawainA有潜力用于膀胱癌的相关研究。
Cas No.3420-72-2
别名2'-羟基-4,4',6'-三甲氧基查耳酮
Canonical SMILESO=C(C1=C(OC)C=C(OC)C=C1O)/C=C/C2=CC=C(OC)C=C2
分子式C18H18O5
分子量314.33
溶解度DMSO: 100 mg/mL (318.14 mM)
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Flavokawain A, a proming anticarcinogenic agent, is a chalcone from kava extract with anti-tumor activity. Flavokawain A induces cell apoptosis by involvement of Bax protein-dependent and mitochondria-dependent apoptotic pathway. Flavokawain A has the potential for the study of bladder cancer[1].

[1]. Xiaolin Zi, et al. Flavokawain A, a novel chalcone from kava extract, induces apoptosis in bladder cancer cells by involvement of Bax protein-dependent and mitochondria-dependent apoptotic pathway and suppresses tumor growth in mice. Cancer Res. 2005 Apr 15;65(8):3479-86.