| CAS NO: | 17605-67-3 |
| 包装 | 价格(元) |
| 5mg | 电议 |
| 10mg | 电议 |
| 20mg | 电议 |
| Cas No. | 17605-67-3 |
| 别名 | 岩皂甾醇,24-ethylidene Cholesterol |
| 化学名 | (3β,24E)-stigmasta-5,24(28)-dien-3-ol |
| Canonical SMILES | C/C=C(C(C)C)\CC[C@@H](C)[C@@]1([H])CC[C@@]2([H])[C@]3([H])CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@@]21C |
| 分子式 | C29H48O |
| 分子量 | 412.7 |
| 溶解度 | 24-ethylidene Cholesterol |
| 储存条件 | 4°C, protect from light |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Fucosterol is a plant sterol found in algae that has diverse biological activities including antioxidant, anti-inflammatory, anticancer, and antidiabetic properties among others.[1] It decreases markers of oxidative damage and increases antioxidative enzyme activity in vitro.[2] It reduces the expression of TNF-α and IL-6 following LPS administration by halting NF-κB and p38 MAPK signaling in RAW 264.7 murine macrophages.[3] In HEK293, MCF-7, and SiHa cells, fucosterol decreases proliferation (IC50s = 185.4, 43.3, and 34.0 μg/ml, respectively).[4] It also has anticancer activity in HL-60 leukemia cells, where it inhibits cell growth, halts the cell cycle at the G2/M transition, and induces apoptosis with maximally increased caspase-9, -8, and -3 expression at 68.8 μM.[5] In a streptozotocin rat model of diabetes, it decreases serum glucose concentrations when administered at 30 mg/kg.[6] Reference: |
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