包装 | 价格(元) |
10mM (in 1mL DMSO) | 电议 |
5mg | 电议 |
10mg | 电议 |
50mg | 电议 |
100mg | 电议 |
Canonical SMILES | NC1=NC(N(C2=CC=CC(C3=CC=CC=C3)=C2)C=C1Cl)=O.Cl |
分子式 | C16H13Cl2N3O |
分子量 | 334.2 |
溶解度 | DMSO : 130 mg/mL (388.99 mM) |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Bobcat339 hydrochloride is a cytosine-based TET enzyme inhibitor with IC50 of 33 μM (TET1) and 73 μM (TET2). It is useful to the field of epigenetics and serves as a starting point for new therapeutics that target DNA methylation and gene transcription. IC50: 33 μM (TET1), 73 μM (TET1)[1] [1]. Chua GNL, et al. Cytosine-Based TET Enzyme Inhibitors. ACS Med Chem Lett. 2019 Jan 31;10(2):180-185. |