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SAICAR(hydrate)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
SAICAR(hydrate)图片
包装:500µg
市场价:4763元

产品介绍
An intermediate for purine synthesis
Canonical SMILESNC1=C(C(N[C@H](C(O)=O)CC(O)=O)=O)N=CN1[C@H]2[C@H](O)[C@H](O)[C@@H](COP(O)(O)=O)O2.O
分子式C13H19N4O12P•XH2O
分子量454.3
溶解度Methanol: Slightly Soluble,Water: Slightly Soluble
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

SAICAR is an intermediate in thede novopurine nucleotide synthesis pathway. It is reported to stimulate pyruvate kinase isoform M2 and to promote cancer cell survival in conditions of limited glucose availability.1

1.Keller, K.E., Tan, I.S., and Lee, Y.S.SAICAR stimulates pyruvate kinase isoform M2 and promotes cancer cell survival in glucose-limited conditionsScience3381069-1072(2012)