| CAS NO: | 124265-89-0 |
| 包装 | 价格(元) |
| 10mM (in 1mL DMSO) | 电议 |
| 5mg | 电议 |
| 10mg | 电议 |
| 25mg | 电议 |
| 50mg | 电议 |
| 100mg | 电议 |
| Cas No. | 124265-89-0 |
| 别名 | H2G |
| Canonical SMILES | O=C1NC(N)=NC2=C1N=CN2C[C@H](CO)CCO |
| 分子式 | C10H15N5O3 |
| 分子量 | 253.26 |
| 溶解度 | DMSO: 230 mg/mL (908.16 mM) |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Omaciclovir (H2G) is a potent and selective inhibitor of herpesvirus replication. Omaciclovir is a nucleoside analog with antiviral activity[1]. Omaciclovir is a nucleoside analog with in vitro inhibitory activity against varicella-zoster virus (VZV), herpes simplex virus types 1 and 2 (HSV-1 and -2), Epstein-Barr virus, and human herpesvirus 6. Omaciclovir is also efficacious in simian varicella virus-infected monkeys[1].Omaciclovir shows antiviral activities against different human herpesviruses with EC50s of 0.72 ± 0.1, 0.62 ± 0.2, 0.015 ± 0.004, 0.048 ± 0.023, 0.047 ± 0.004, 0.035 ± 0.022, and 0.016 ± 0.003 μM for MRC-5 VZV-32, MRC-5 Molly, MeWo VZV-32, MeWo Molly, MeWo Emily, MeWo VZ11, and MeWo VZ30, respectively[1]. [1]. T I Ng , et al. Selection and Characterization of Varicella-Zoster Virus Variants Resistant to (R)-9-[4-hydroxy-2-(hydroxymethy)butyl]guanine. Antimicrob Agents Chemother. 2001 Jun;45(6):1629-36. |
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