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2-Aminoimidazole
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
2-Aminoimidazole图片
CAS NO:7720-39-0
包装:250mg
市场价:450元

产品介绍
2-Aminoimidazole是一种有效的抗生物膜剂,可用作抗菌佐剂。2-Aminoimidazole通过抑制生物被膜的形成和基因编码的抗生素抗性特征来破坏细菌自我保护的能力。2-Aminoimidazole也是一种弱的非竞争性人精氨酸酶I(humanarginaseI)抑制剂,Ki值为3.6mM。
Cas No.7720-39-0
别名2-氨基咪唑
Canonical SMILESNC1=NC=CN1
分子式C3H5N3
分子量83.09
储存条件4°C, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

2-Aminoimidazole is a potent antibiofilm agent that can be used as an adjuvant to antimicrobial. 2-aminoimidazoles disrupts the ability of bacteria to protect themselves by inhibiting biofilm formation and genetically-encoded antibiotic resistance traits. 2-Aminoimidazole is also a weak noncompetitive inhibitor of human arginase I with a Ki of 3.6 mM[1][2][3].

[1]. Thompson RJ, et, al. Identification of BfmR, a response regulator involved in biofilm development, as a target for a 2-Aminoimidazole-based antibiofilm agent. Biochemistry. 2012 Dec 11;51(49):9776-8. [2]. Jacobs L, et, al. 2-Aminoimidazoles as potent inhibitors of contaminating brewery biofilms. Biofouling. 2021 Feb 11;1-17. [3]. Ilies M, et, al. 2-aminoimidazole amino acids as inhibitors of the binuclear manganese metalloenzyme human arginase I. J Med Chem. 2010 May 27;53(10):4266-76.