CAS NO: | 146877-98-7 |
包装 | 价格(元) |
500mg | 电议 |
1g | 电议 |
5g | 电议 |
Cas No. | 146877-98-7 |
Canonical SMILES | O[C@H]1C[C@H](N2C=NC3=C2N=C(N)NC3=O)O[C@@H]1COP([O-])([O-])=O.[Na+].[Na+].O |
分子式 | C10H12N5O7P•2Na [XH2O] |
分子量 | 391.2 |
溶解度 | PBS (pH 7.2): 10 mg/ml |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | 2'-Deoxyguanosine 5'-monophosphate (dGMP) is used as a substrate of guanylate kinases to generate dGDP, which in turn is phosphorylated to dGTP, a nucleotide precursor used in DNA synthesis. In addition, dGMP can be efficiently phosphorylated by the type I thymidylate kinase of the malarial agent P. falciparum. In humans, deficiency of mitochondrial deoxyguanosine kinase, which synthesizes dGMP from ATP and deoxyguanosine, contributes to mitochondrial DNA depletion syndrome. |