NSC 624206 是一种泛素 E1 (UBA1) 抑制剂,IC50 为 ~9 μM。 NSC 624206 特异性阻断泛素-硫酯形成 (IC50\u003d13 μM),但对泛素腺苷酸化没有影响。
Cas No. | 13116-77-3 |
化学名 | N-(3-(4-chlorophenyl)-3,3-dimercaptopropyl)decan-1-aminium chloride |
Canonical SMILES | ClC1=CC=C(C=C1)C(S)(CC[NH2+]CCCCCCCCCC)S.[Cl-] |
分子式 | C19H32ClNS2.HCl |
分子量 | 410.51 |
溶解度 | DMF: 0.16 mg/ml,DMSO: 1 mg/ml,Ethanol: 1 mg/ml |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |