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SIS3
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
SIS3图片
CAS NO:521984-48-5
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议

产品名称
SIS 3
产品介绍

生物活性

SIS3是Smad3的新型特异性抑制剂。它对转化生长因子-β1诱导的细胞外基质表达有影响。

靶点信息

Smad3

化学数据

目录号A16065
作用机制Inhibitor (抑制剂)
M. Wt489.99
FormulaC28H27N3O3.HCl
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.521984-48-5
SynonymsSIS 3
SMILESCN1C(C2=CC=CC=C2)=C(C3=C1N=CC=C3)/C([H])=C([H])/C(N4CCC5=CC(OC)=C(OC)C=C5C4)=O.Cl

溶解度

In vitro (25°C)DMSO92 mg/mL (187.76 mM)
WaterInsoluble
Ethanol23 mg/mL (46.94 mM)
In vivo2% DMSO+30% PEG 300+2% Tween 80+ddH2O4 mg/mL
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM20.41 mL102.04 mL204.09 mL
0.5 mM4.08 mL20.41 mL40.82 mL
1 mM2.04 mL10.2 mL20.41 mL
5 mM0.41 mL2.04 mL4.08 mL

*The above data is based on the productmolecular weight 489.99. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.