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Picosulfate(sodium salt hydrate)
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Picosulfate(sodium salt hydrate)图片
CAS NO:1307301-38-7
包装与价格：
包装价格(元)
50mg电议
100mg电议
250mg电议
500mg电议

产品介绍
A stimulant laxative and prodrug form of desacetyl bisacodyl
Cas No.1307301-38-7
别名匹可硫酸钠一水合物
Canonical SMILESO=S([O-])(OC1=CC=C(C(C2=CC=C(C=C2)OS(=O)([O-])=O)C3=CC=CC=N3)C=C1)=O.[Na+].[Na+].O
分子式C18H13NO8S2·2Na [H2O]
分子量499.4
溶解度: ,DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 1 mg/ml,PBS (pH 7.2): 10 mg/ml
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Picosulfate is a stimulant laxative and prodrug form of desacetyl bisacodyl .1Unlike bisacodyl , picosulfate is hydrolyzed to DAB by colonic microbiota. Picosulfate (5 mg/kg) increases excreted fecal weight in a rat model of loperamide-induced constipation.2Formulations containing picosulfate have been used for colonoscopy preparation.

1.Twycross, R., Sykes, N., Mihalyo, M., et al.Stimulant laxatives and opioid-induced constipationJ. Pain Symptom Manage.43(2)306-313(2012) 2.MÉitÉ, S., Bahi, C., YÉo, D., et al.Laxative activities of Mareya micrantha (Benth.) MÜll. Arg. (Euphorbiaceae) leaf aqueous extract in ratsBMC Complement. Altern. Med.107(2010)