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A-943931(hydrochloride hydrate)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
A-943931(hydrochloride hydrate)图片
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议
25mg电议

产品介绍
A histamine H4receptor antagonist
Canonical SMILESNC1=NC(N2CC[C@H](C2)N)=C(CCCC3=CC=CC=C34)C4=N1.O.Cl.Cl
分子式C17H21N5·2HCl [XH2O]
分子量368.3
溶解度Water: 100 mM
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

A-943931 is a histamine H4receptor antagonist (Ki= 3.8 nM).1In vivo, A-943931 inhibits scratching induced by clobenpropit in mice (ED50= 26 µmoles/kg, i.p.).

1.Milicic, I., Witte, D.G., Miller, T.L., et al.Identification of two potent and selective histamine H4 receptor antagonists with antipruritic activityFASEB J.23(S1)760.768-760.768(2009)