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Betazole
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Betazole图片
CAS NO:105-20-4
包装与价格：
包装价格(元)
10mg电议
50mg电议

产品介绍
Betazole(Ametazole)是一种吡唑类组胺，是一种口服活性H2受体激动剂。Betazole诱导胃酸分泌，导致胆总管压力立即显著升高。Betazole被用作一种被称为histalog的诊断剂，用于研究胃酸分泌能力。
Cas No.105-20-4
别名倍他唑,Ametazole
Canonical SMILESNCCC1=NNC=C1
分子式C5H9N3
分子量111.15
溶解度DMSO: 250 mg/mL (2249.21 mM)
储存条件4℃, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Betazole (Ametazole), a pyrazole analogue of histamine, is an orally active histamine H2 receptor agonist. Betazole induces gastric acid secretion and causes an immediate and significant increase in common bile duct pressure. Betazole is used as a diagnostic agent known as histalog for investigating gastric acid secretory capacity[1][2][3].

Betazole (Ametazole) is a weak histamine agonist with relative selectivity towards H2 receptors and only minimal H1 activity. Betazole induces gastric inhibitory polypeptide (GIP) secretion[1].

[1]. Maples MD, Effects of betazole hydrochloride and cimetidine on common bile pressure and duodenal myoelectric activity in the dog. Am Surg. 1981;47(12):519-521. [2]. Spitz IM, Betazole-induced GIP secretion is not mediated by gastric HCl. Metabolism. 1982;31(4):380-382. [3]. CLAYMAN CB,. A simple oral gastric secretory stimulant (betazole hydrochloride). JAMA. 1961;175:908-909.