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Tos-PEG3-CH2COOH
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Tos-PEG3-CH2COOH图片
CAS NO:1581248-63-6
包装:1g
市场价:9857元

产品介绍
Tos-PEG3-CH2COOH 是一种 PROTAC linker，属于 PEG 类。可用于合成 PROTAC 分子。
Cas No.1581248-63-6
分子式C15H22O8S
分子量362.4
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Tos-PEG3-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[1]. Snaebjornsson MT, et al. Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways. Exp Mol Med. 2018 Apr 16;50(4):34.