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DL-Laudanosine
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
DL-Laudanosine图片
CAS NO:1699-51-0
包装:100mg
市场价:2250元

产品介绍
DL-Laudanosine 是 Atracurium 和 Cisatracurium 的代谢物，可透过血脑屏障，引起兴奋和癫痫发作。
Cas No.1699-51-0
Canonical SMILESCOC1=CC(CC2N(CCC3=C2C=C(C(OC)=C3)OC)C)=CC=C1OC
分子式C21H27NO4
分子量357.44
溶解度DMSO : 100 mg/mL (279.77 mM)
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

DL-Laudanosine, an Atracurium and Cisatracurium metabolite, crosses the blood-brain barrier and may cause excitement and seizure activity[1].

DL-Laudanosine (Laudanosine) appears to be unique in its ability to produce cerebral stimulation in lightly anaesthetized animals and it is reported to cause arousal from anaesthesia in subconvulsive doses[1].

References:
[1]. V Fodale, et al. Laudanosine, an Atracurium and Cisatracurium Metabolite. Eur J Anaesthesiol. 2002 Jul;19(7):466-73.
[2]. D J Chapple, et al. Cardiovascular and Neurological Effects of Laudanosine. Studies in Mice and Rats, and in Conscious and Anaesthetized Dogs. Br J Anaesth. 1987 Feb;59(2):218-25.