CAS NO: | 883226-64-0 |
包装 | 价格(元) |
10mg | 电议 |
50mg | 电议 |
Cas No. | 883226-64-0 |
Canonical SMILES | CC2=C(CNC(NCC3=CC=CS3)=O)C1=CC=CC=C1O2 |
分子式 | C16H16N2O2S |
分子量 | 300.38 |
溶解度 | Soluble in DMSO |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Inverse agonist of the constitutive androstane receptor (CAR). Inhibits CAR activity via recruitment of nuclear receptor co-repressor (NCoR). Suppresses CITCO-induced CYP2B6 gene expression in human primary hepatocytes. Küblbeck et al (2011) New in vitro tools to study human constitutive androstane receptor (CAR) biology: discovery and comparison of human CAR inverse agonists. Mol.Pharm. 8 2424 PMID:22044162 |