CAS NO: | 1507367-00-1 |
包装: | 1mg |
市场价: | 3425元 |
Cas No. | 1507367-00-1 |
Canonical SMILES | C#CC1=C2C(NC=N2)=NC(NC3=CC=CC(CC(N)=O)=C3)=N1 |
分子式 | C15H12N6O |
分子量 | 292.3 |
溶解度 | DMSO: 25 mg/ml |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Potent and reversible NIMA related kinase 2 (Nek2) inhibitor (IC50 = 56 nM). Induces increased mitotic abnormalities and mitotic delay. Cell permeable and active in vivo. Lebraud et al (2014) Model system for irreversible inhibition of Nek2: thiol addition to ethynylpurines and related substituted heterocycles. Org.Biomol.Chem. 12 141 PMID:24213855 |