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Betulin 3,28-diacetate
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Betulin 3,28-diacetate图片
CAS NO:1721-69-3
包装与价格：
包装价格(元)
1mg电议
5mg电议
10mg电议
25mg电议

产品介绍
A triterpene with antiviral and hepatoprotective activities
Cas No.1721-69-3
别名桦木脑二乙酸,Betulin 3,28-diacetate
Canonical SMILESC[C@]1([C@]2([C@]([C@@]3([C@@](C(C)([C@H](CC3)OC(C)=O)C)([H])CC2)C)([H])CC4)C)[C@@]4([H])[C@]([C@@H](CC5)C(C)=C)([H])[C@@]5(COC(C)=O)CC1
分子式C34H54O4
分子量526.8
溶解度Chloroform: 10 mg/ml,DMF: slightly soluble,DMSO: slightly soluble
储存条件4°C, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Betulin 3,28-diacetate is a triterpene and derivative of betulin that has been found inB. pendulaand has antiviral and hepatoprotective activities.1,2,3It inhibits Semliki Forest virus (SFV) replication in virus-infected Huh7 cells (IC50= 9.1 µM).2Betulin 3,28-diacetate (20 mg/kg) increases the rate of bile secretion, a marker of hepatic function, in rat models of hepatitis induced by carbon tetrachloride, ethanol, or tetracycline .3

1.Salah, A., and Bakibaev, A.Effective method of extraction of betulin diacetate from birch barkJ. Nat. Prod. Resour.3(1)90-93(2017) 2.Pohjala, L., Alakurtti, S., Ahola, T., et al.Betulin-derived compounds as inhibitors of alphavirus replicationJ. Nat. Prod.72(11)1917-1926(2009) 3.Flekhter, O.B., Karachurina, L.T., Poroikov, V.V., et al.The synthesis and hepatoprotective activity of esters of the lupane group triterpenoidsRuss. J. Bioorg. Chem.26(3)192-200(2000)