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Cefsulodin(sodium salt hydrate)
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Cefsulodin(sodium salt hydrate)图片
CAS NO:1426397-23-0
包装与价格：
包装价格(元)
100mg电议
250mg电议
500mg电议
1g电议

产品介绍
A βlactam antibiotic
Cas No.1426397-23-0
别名头孢磺吡苄钠盐
Canonical SMILESO=C(N[C@@H]1C(N2[C@]1([H])SCC(C[N+]3=CC=C(C(N)=O)C=C3)=C2C([O-])=O)=O)[C@H](S([O-])(=O)=O)C4=CC=CC=C4.[Na+].O
分子式C22H19N4O8S2•Na [XH2O]
分子量531.5
溶解度DMSO: 0.1 mg/ml,PBS (pH 7.2): 10 mg/ml
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Cefsulodin is a β-lactam antibiotic that lyses actively-growingE. coliby binding specifically to the intermembrane proteins, penicillin-binding proteins 1a and b, whose transglycosylase and transpeptidase activities are involved in cell elongation and septation.1Cefsulodin has been used in combination with other β-lactam antibiotics, such as cefazolin as a strategy to circumvent drug resistance.2

1.Jacoby, G.H., and Young, K.D.Cell cycle-independent lysis of Escherichia coli by cefsulodin, an inhibitor of penicillin-binding proteins 1a and 1bJournal of Bacteriology173(1)1-5(1991) 2.Sarkar, S.K., Dutta, M., Kumar, A., et al.Sub-inhibitory cefsulodin sensitization of E. coli to ß-lactams is mediated by PBP1b inhibitionPLoS One7(11)(2012)