Cas No. | 2141978-86-9 |
Canonical SMILES | OC1(C2=CC=C(Br)C=C2)CCN(C(/C(=C/C3=CC=CC=C3)/NC(=O)C4=CC=CC=C4)=O)CC1 |
分子式 | C27H25BrN2O3 |
分子量 | 505.41 |
溶解度 | DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Viral RNA synthesis inhibitor; targets membrane-bound coronaviral RNA replication by inhibiting double membrane vesicle (DMV) formation. Inhibits HCoV-229E infection of MRC-5 cells in a plaque forming assay (IC50 = 0.7 μM). Also inhibits HCoV-229E and MERS-CoV replication in human airway epithelia cultures. |