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Endosulfan sulfate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Endosulfan sulfate图片
CAS NO:1031-07-8
包装与价格:
包装价格(元)
50mg电议
100mg电议

产品介绍
硫丹硫酸盐是杀虫剂硫丹的主要代谢物,用于多种作物。
Cas No.1031-07-8
别名硫丹硫酸酯
Canonical SMILESClC1(C2(Cl)Cl)C(COS(OC3)(=O)=O)C3C2(Cl)C(Cl)=C1Cl
分子式C9H6Cl6O4S
分子量422.9
溶解度DMSO: Slightly Soluble,Methanol: Slightly Soluble
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Endosulfan sulfate is a major metabolite of endosulfan, a broad-spectrum organochlorine insecticide.1Endosulfan sulfate is formed through oxidation of endosulfan by bacteria and fungi in the environment, where it is considered a persistent organic pollutant (POP). It accumulates in the liver and gonads of wild silverside fish (O. bonariensis) and is found in higher amounts in mature fish than pre-spawning fish.2Levels of endosulfan sulfate in the gills of matureO. bonariensiscorrelate with increased levels of lipid peroxidation. It is toxic to freshwater fish, includingG. affinis,H. formosa,P. latipinna, andP. promelas, with LC50values ranging from 2.1 to 3.5 µg/L after a 96-hour exposure.3Endosulfan sulfate is the main metabolite found in the liver of mice following endosulfan administration at doses of 0.3 and 3 mg/kg.4It decreases the levels of glutathione (GSH) and malondialdehyde (MDA), a product of lipid peroxidation, in the liver, but increases MDA in the kidney when administered at a dose of 3 mg/kg.

1.Kataoka, R., and Takagi, K.Biodegradability and biodegradation pathways of endosulfan and endosulfan sulfateAppl. Microbiol. Biotechnol.97(8)3285-3292(2013) 2.Barni, M.F.Assessment of persistent organic pollutants accumulation and lipid peroxidation in two reproductive stages of wild silverside (Odontesthes bonariensis)Ecotoxicol. Environ. Saf.9945-53(2014) 3.Carriger, J.F., Hoang, T.C., Rand, G.M., et al.Acute toxicity and effects analysis of endosulfan sulfate to freshwater fish speciesArch. Environ. Contam. Toxicol.60(2)281-289(2011) 4.Yan, J., Wang, D., Miao, J., et al.Discrepant effects of α-endosulfan, β-endosulfan, and endosulfan sulfate on oxidative stress and energy metabolism in the livers and kidneys of miceChemosphere205223-233(2018)