CAS NO: | 143615-69-4 |
包装: | 1mg |
市场价: | 2722元 |
Cas No. | 143615-69-4 |
Canonical SMILES | CC(N[C@@H](CO)[C@@H](O)/C=C/CCCCCCCCCCCCC)=O |
分子式 | C20H39NO3 |
分子量 | 341.5 |
溶解度 | Chloroform: soluble,DMF: 5 mg/ml,DMSO: soluble,Ethanol: soluble |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | C2 L-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides. It stimulates cholesterol efflux in CHO cells expressing the human ABCA1 receptor when used at a concentration of 10 μM, however, this efflux is 50% less than that stimulated by C2 ceramide . C2 L-threo Ceramide inhibits IL-4 production by 17% in EL4 T cells stimulated with phorbol 12-myristate 13-acetate when used at a concentration of 10 μM. It also induces cell cycle arrest in the G0/G1 phase and a 7-fold increase in sphingosine accumulation as well as inhibits growth of HL-60 leukemia cells. |