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C2 L-threo Ceramide(d18:1/2:0)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
C2 L-threo Ceramide(d18:1/2:0)图片
CAS NO:143615-69-4
包装:1mg
市场价:2722元

产品介绍
Cas No.143615-69-4
Canonical SMILESCC(N[C@@H](CO)[C@@H](O)/C=C/CCCCCCCCCCCCC)=O
分子式C20H39NO3
分子量341.5
溶解度Chloroform: soluble,DMF: 5 mg/ml,DMSO: soluble,Ethanol: soluble
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

C2 L-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides. It stimulates cholesterol efflux in CHO cells expressing the human ABCA1 receptor when used at a concentration of 10 μM, however, this efflux is 50% less than that stimulated by C2 ceramide . C2 L-threo Ceramide inhibits IL-4 production by 17% in EL4 T cells stimulated with phorbol 12-myristate 13-acetate when used at a concentration of 10 μM. It also induces cell cycle arrest in the G0/G1 phase and a 7-fold increase in sphingosine accumulation as well as inhibits growth of HL-60 leukemia cells.