CAS NO: | 1394121-05-1 |
包装 | 价格(元) |
250mg | 电议 |
500mg | 电议 |
Cas No. | 1394121-05-1 |
Canonical SMILES | OC1(C#CC2=CC=C3N=C(NCCOC)N(C4=NC(N)=NC=C4)C3=C2)CCCCC1 |
分子式 | C22H26N6O2 |
分子量 | 406.48 |
溶解度 | DMSO: 270 mg/mL (664.24 mM) |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | PAK-IN-1 is a PAK inhibitor that displays group II selectivity. PAK-IN-1 inhibits PAK4, PAK5 and PAK6 with IC50s of 7.5, 36, 126 nM, respectively. PAK-IN-1 is compound 4 from the reference[1]. [1]. Karpov AS, et al. Optimization of a Dibenzodiazepine Hit to a Potent and Selective Allosteric PAK1 Inhibitor. ACS Med Chem Lett. 2015 May 22;6(7):776-81. |