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1-Palmitoyl-d9 Lysophosphatidic Acid
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
1-Palmitoyl-d9 Lysophosphatidic Acid图片
包装与价格:
包装价格(元)
25 µg电议
50 µg电议
100 µg电议

产品介绍
An internal standard for the quantification of 1-palmitoyl lysophosphatidic acid
Canonical SMILESO[C@@H](COP(O)(O)=O)COC(CCCCCCCCCCCC([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])=O
分子式C19H30D9O7P
分子量419.5
溶解度Ethanol: 10mg/ml
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

1-Palmitoyl-d9lysophosphatidic acid (1-palmitoyl-d9LPA) is intended for use as an internal standard for the quantification of 1-palmitoyl LPA by GC- or LC-MS. 1-Palmitoyl LPA is an analog of LPA that contains palmitic acid at thesn-1 position. It induces reporter gene expression in PC12 cells expressing human lysophosphatidic acid receptor 4 (LPA4) when used at concentrations ranging from 0.01 to 10 µM.11-Palmitoyl LPA (12-300 µM) induces aggregation of isolated human platelets, an effect that can be reversed by prostaglandin E1, theophylline , or EDTA.2It also binds to calcium and magnesium and enhances the activity of ampicillin , piperacillin , and ceftazidime againstP. aeruginosaisolates from patients with cystic fibrosis.3

1.Noguchi, K., Ishii, S., and Shimizu, T.Identification of p2y9/GPR23 as a novel G protein-coupled receptor for lysophosphatidic acid, structurally distant from the Edg familyJ. Biol. Chem.278(28)25600-25606(2003) 2.Gerrard, J.M., Kindom, S.E., Peterson, D.A., et al.Lysophosphatidic acids. Influence on platelet aggregation and intracellular calcium fluxAm. J. Pathol.96(2)423-438(1979) 3.Krogfelt, K.A., Utley, M., Krivan, H.C., et al.Specific phospholipids enhance the activity of β-lactam antibiotics against Pseudomonas aeruginosaJ. Antimicrob. Chemother.46(3)377-384(2000)