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Varenicline-d4
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Varenicline-d4图片
CAS NO:2183239-01-0
包装与价格:
包装价格(元)
500 μg电议
1mg电议

产品介绍
An internal standard for the quantification of varenicline
Cas No.2183239-01-0
别名伐尼克兰-D4,CP 526555-d4
Canonical SMILES[2H]C1([2H])NC([2H])([2H])C2C3=CC4=C(N=CC=N4)C=C3C1C2
分子式C13H9D4N3
分子量215.3
溶解度Water: 0.0877 mg/mL
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Varenicline-d4is intended for use as an internal standard for the quantification of varenicline by GC- or LC-MS. Varenicline is a full agonist of α7 subunit-containing neuronal nicotinic acetylcholine receptors (nAChRs; EC50= 18 µM) and a partial agonist of α4β2 subunit-containing nAChRs (EC50= 2.3 µM).1Formulations containing varenicline have been used as aids in smoking cessation.

1.Mihalak, K.B., Carroll, F.I., and Luetje, C.W.Varenicline is a partial agonist at α4β2 and a full agonist at α7 neuronal nicotinic receptorsMol. Pharm.70(3)801-805(2006)