CAS NO: | 2183239-01-0 |
包装 | 价格(元) |
500 μg | 电议 |
1mg | 电议 |
Cas No. | 2183239-01-0 |
别名 | 伐尼克兰-D4,CP 526555-d4 |
Canonical SMILES | [2H]C1([2H])NC([2H])([2H])C2C3=CC4=C(N=CC=N4)C=C3C1C2 |
分子式 | C13H9D4N3 |
分子量 | 215.3 |
溶解度 | Water: 0.0877 mg/mL |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Varenicline-d4is intended for use as an internal standard for the quantification of varenicline by GC- or LC-MS. Varenicline is a full agonist of α7 subunit-containing neuronal nicotinic acetylcholine receptors (nAChRs; EC50= 18 µM) and a partial agonist of α4β2 subunit-containing nAChRs (EC50= 2.3 µM).1Formulations containing varenicline have been used as aids in smoking cessation. 1.Mihalak, K.B., Carroll, F.I., and Luetje, C.W.Varenicline is a partial agonist at α4β2 and a full agonist at α7 neuronal nicotinic receptorsMol. Pharm.70(3)801-805(2006) |