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Aurantio-obtusin
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Aurantio-obtusin图片
CAS NO:67979-25-3
包装:20mg
市场价:2000元

产品介绍
Aurantio-obtusin 是一种从决明子中分离的蒽醌，具有抗炎、抗氧化、抗凝血和抗高血压活性。
Cas No.67979-25-3
别名橙黄决明素
化学名1,3,7-trihydroxy-2,8-dimethoxy-6-methylanthracene-9,10-dione
Canonical SMILESCC1=C(C(=C2C(=C1)C(=O)C3=CC(=C(C(=C3C2=O)O)OC)O)OC)O
分子式C17H14O7
分子量330.28
溶解度≥ 33mg/mL in DMSO
储存条件4°C, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Aurantio-obtusin is an anthraquinone isolated from Semen Cassiae, with anti-Inflammatory, anti-oxidative, anti-coagulating and anti-hypertension activities[1][2][3]. Aurantio-obtusin relaxes systemic arteries through endothelial PI3K/AKT/eNOS-dependent signaling pathway in rats, thus acts as a new potential vasodilator[2]. Aurantio-obtusin inhibits allergic responses in IgE-mediated mast cells and anaphylactic models and is potential for treatment for allergy-related diseases[3].

References:
[1]. Hou J, et al. Anti-Inflammatory Effects of Aurantio-Obtusin from Seed of Cassia obtusifolia L. through Modulation of the NF-κB Pathway. Molecules. 2018 Nov 27;23(12).
[2]. Li S, et al. Aurantio-obtusin relaxes systemic arteries through endothelial PI3K/AKT/eNOS-dependent signaling pathway in rats. J Pharmacol Sci. 2015 Jul;128(3):108-15.
[3]. Kim M, et al. Cassia tora Seed Extract and Its Active Compound Aurantio-obtusin Inhibit Allergic Responses in IgE-Mediated Mast Cells and Anaphylactic Models. J Agric Food Chem. 2015 Oct 21;63(41):9037-46.