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Pifithrin-μ(NSC-303580)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Pifithrin-μ(NSC-303580)图片
CAS NO:64984-31-2
规格:≥98%
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议
100mg电议
250mg电议
500mg电议
1g电议

产品介绍
理化性质和储存条件
Molecular Weight (MW)181.21
FormulaC8H7NO2S
CAS No.64984-31-2
Storage-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)DMSO: 36 mg/mL (198.7 mM)
Water: <1 mg/mL (slightly soluble or insoluble)
Ethanol: N/A
Solubility (In vivo)1% DMSO+30% polyethylene glycol+1% Tween 80:10 mg/mL
SynonymsPifithrin-μ; Pifithrin μ; Pifithrinμ; 2-Phenylethynesulfonamide; PFT-μ; PFT μ; PFTμ; NSC303580; NSC-303580; NSC 303580
实验参考方法
GeneralPifithrin-μ (40 mg/kg, ip) produces protective effect from p53-dependent apoptosis in C57B1/6J mice of 8 or 9 Gy of total body gamma radiation. In a xenograft mouse model, Pifithrin-μ significantly enhances the inhibition of TRAIL on MiaPaca-2 tumor growth
Animal model C57B1/6J mice.
Formulation DMSO
Dosages 40 mg/kg
Administration i.p
References[1] Strom E, et al. Nat Chem Biol. 2006, 2(9), 474-479.
生物活性

Blood Cancer J. 2011 Jul; 1(7): e28.