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Salbutamol(hydrochloride)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Salbutamol(hydrochloride)图片
CAS NO:50293-90-8
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议

产品介绍
Levalbuterol ((R)-Albuterol) hydrochloride 是一种短效 β2-adrenergic receptor 激动剂和沙丁胺醇的活性 (R)-对映异构体。
Cas No.50293-90-8
别名盐酸左旋沙丁胺醇,(R)-Albuterol hydrochloride; (R)-Salbutamol hydrochloride; Levosalbutamol hydrochloride
Canonical SMILESOCC1=C(O)C=CC([C@@H](O)CNC(C)(C)C)=C1.Cl
分子式C13H21NO3•HCl
分子量275.8
溶解度DMF: 25 mg/ml,DMSO: 20 mg/ml,Ethanol: 12 mg/ml,PBS (pH 7.2): 3 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Salbutamol is an agonist of the β2-adrenergic receptor (β2-AR; Kd = 759 nM in a radioligand binding assay using CHO cells expressing the human receptor). It is selective for β2-ARs over β1- and β3-ARs (Kds = 46.8 and 21.9 μM, respectively). Salbutamol (25-50 μg/kg, i.v.) reduces acetylcholine-induced bronchospasm in anesthetized guinea pigs. It also reduces response of bronchial muscle to efferent vagal stimulation in anesthetized cats and dogs when administered at doses ranging from 1 to 2.5 and 10 to 20 μg/kg, respectively. Nebulized salbutamol reduces transpulmonary pressure in recurrent airway obstruction-affected horses (EC50 = 39.7 μg). Formulations containing salbutamol have been used in the treatment of asthma and chronic obstructive pulmonary disease (COPD).