| CAS NO: | 2361327-08-2 |
| 包装 | 价格(元) |
| 1mg | 电议 |
| 5mg | 电议 |
| 10mg | 电议 |
| Cas No. | 2361327-08-2 |
| Canonical SMILES | O=C1C2=C(CCN(C(C3=CC=C(C(O)=O)C=C3)=O)C2)C4=C(C=CC=C4)O1 |
| 分子式 | C20H15NO5 |
| 分子量 | 349.3 |
| 溶解度 | DMSO: soluble,Methanol: soluble |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | DS44960156 is an inhibitor of methylenetetrahydrofolate dehydrogenase 2 (MTHFD2; IC50= 1.6 µM).1It is selective for MTHFD2 over MTHFD1 (IC50= >30 µM). 1.Kawai, J., Ota, M., Ohki, H., et al.Structure-based design and synthesis of an isozyme-selective MTHFD2 inhibitor with a tricyclic coumarin scaffoldACS Med. Chem. Lett.10(6)893-898(2019) |
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