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Coenzyme A(lithium salt hydrate)
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Coenzyme A(lithium salt hydrate)图片
包装与价格：
包装价格(元)
25mg电议
50mg电议
100mg电议
250mg电议

产品介绍
An essential cofactor in enzymatic acetyl transfer reactions
Canonical SMILESO[C@H]1[C@H](N2C=NC3=C2N=CN=C3N)O[C@H](COP(OP(OCC(C)(C)[C@@H](O)C(NCCC(NCCS)=O)=O)([O-])=O)([O-])=O)[C@H]1OP([O-])(O)=O.[Li+].[Li+].[Li+].OO[C@H]1[C@H](N2C=NC3=C2N=CN=C3N)O[C@H](COP(OP(OCC(C)(C)[C@@H](O)C(NCCC(NCCS)=O)=O)([O-])=O)([O-])=O)[C@H]1OP([O-])(O)=O.[Li+].[Li+].[Li+].O
分子式C21H33N7O16P3S.3Li [XH2O]
分子量785.3
溶解度PBS (pH 7.2): 10 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Coenzyme A (CoA) is an essential cofactor functioning as an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism.1About 4% of cellular enzymes utilize CoA as a substrate. It is synthesized from pantothenic acid in a five-step process that requires ATP.2The pantothenate kinase step of the CoA biosynthetic pathway has been identified as a target for the development of antibacterial compounds.3

1.Leonardi, R., Zhang, Y.M., Rock, C.O., et al.Coenzyme A: Back in actionProg. Lipid Res.44(2-3)125-153(2005) 2.Jackowski, S.Biosynthesis of pantothenic acid and coenzyme AEscherichia coli and Salmonella typhimurium: Cellular and molecular biology687-694(1996) 3.Begley, T.P., Kinsland, C., and Strauss, E.The biosynthesis of coenzyme A in bacteriaVitamins and Hormones61157-171(2001)