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Eriocitrin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Eriocitrin图片
CAS NO:13463-28-0
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
1mg电议
5mg电议
10mg电议
20mg电议

产品介绍
Eriocitrin 是一种从柠檬中分离出来的黄酮类化合物,它是一种强效的抗氧化剂。Eriocitrin 通过上调 p53,cyclin A,cyclin D3 和CDK6 使 S 期细胞周期停滞,从而抑制肝癌细胞的增殖。Eriocitrin 通过激活线粒体涉及的内在信号传导途径来触发细胞凋亡。
Cas No.13463-28-0
别名圣草次甙
Canonical SMILESO=C(C[C@@H](C1=CC(O)=C(O)C=C1)OC2=CC(O[C@@H]([C@@H]([C@@H](O)[C@@H]3O)O)O[C@@H]3CO[C@H](O[C@@H](C)[C@H](O)[C@H]4O)[C@@H]4O)=C5)C2=C5O
分子式C27H32O15
分子量596.53
溶解度DMSO: 125 mg/mL (209.55 mM)
储存条件4°C, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Eriocitrin is a flavonoid isolated from lemon, which is a strong antioxidant agent. Eriocitrin could inhibit the proliferation of hepatocellular carcinoma cell lines by arresting cell cycle in S phase through up-regulation of p53, cyclin A, cyclin D3 and CDK6. Eriocitrin triggers apoptosis by activating mitochondria-involved intrinsic signaling pathway[1].

[1]. Wang Z, et al. Eriocitrin from lemon suppresses the proliferation of human hepatocellular carcinoma cells through inducing apoptosis and arresting cell cycle. Cancer Chemother Pharmacol. 2016 Dec;78(6):1143-1150.