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Apixaban-13C-d3
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Apixaban-13C-d3图片
CAS NO:1261393-15-0
包装与价格:
包装价格(元)
500 μg电议
1mg电议
5mg电议

产品介绍
Apixaban-13C-d3 (BMS-562247-01-13C,d3) 是一种氘和 13C 标记的 Apixaban。
Cas No.1261393-15-0
别名阿哌沙班杂质13C-D3,BMS-562247-01-13C,d3
Canonical SMILESO=C1CCCCN1C2=CC=C(N3CCC(C(C(N)=O)=NN4C5=CC=C(O[13C]([2H])([2H])[2H])C=C5)=C4C3=O)C=C2
分子式C24[13C]H22D3N5O4
分子量463.5
溶解度DMF: 3 mg/ml,DMSO: 5 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Apixaban-13C-d3is intended for use as an internal standard for the quantification of apixaban by GC- or LC-MS. Apixaban is an orally bioavailable, selective inhibitor of both free and prothrombinase-bound factor Xa (Kis = 0.8 nM).1In vivo, apixaban has antithrombotic effects in a rabbit model of venous thrombosis.

1.Turpie, A.G.G.Oral, direct factor Xa inhibitors in development for the prevention and treatment of thromboembolic diseasesArterioscler. Thromb. Vasc. Biol.27(6)1238-1247(2007)