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7-Biopterin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
7-Biopterin图片
CAS NO:2636-52-4
包装与价格:
包装价格(元)
500 μg电议
1mg电议
5mg电议
10mg电议

产品介绍
A pterin
Cas No.2636-52-4
Canonical SMILESO=C1N=C(N)N=C2NC([C@@H](O)[C@@H](O)C)=CN=C21
分子式C9H11N5O3
分子量237.2
溶解度aqueous acid: slightly soluble
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

7-Biopterin is a 7-substituted pterin.1It is formed by non-enzymatic rearrangement of 4a-hydroxy-tetrahydropterin in the absence of pterin-4a-carbinolamine dehydratase (PCD)in vitroand levels are elevated in the urine of hyperphenylalaninemia patients carrying heterozygous mutations in the PCBD gene encoding PCD.1,2

1.ThÖny, B., Neuheiser, F., Kierat, L., et al.Hyperphenylalaninemia with high levels of 7-biopterin is associated with mutations in the PCBD gene encoding the bifunctional protein pterin-4a-carbinolamine dehydratase and transcriptional coactivator (DCoH)Am. J. Hum. Genet.62(6)1302-1311(1998) 2.Curtius, H.C., Kuster, T., Matasovic, A., et al.Primapterin, anapterin, and 6-oxo-primapterin, three new 7-substituted pterins identified in a patient with hyperphenylalaninemiaBiochem. Biophys. Res. Commun.153(2)715-721(1988)