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Tris(2,4-di-tert-butylphenyl)phosphate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Tris(2,4-di-tert-butylphenyl)phosphate图片
CAS NO:95906-11-9
包装:100mg
市场价:990元

产品介绍
Tris(2,4-di-tert-butylphenyl)phosphate是从VitexnegundoL.中分离的一种活性化合物,具有抗炎活性,并通过分子对接抑制了分泌性磷脂酶A2(sPLA2)。
Cas No.95906-11-9
别名三(2,4-二-叔丁基苯基)磷酸酯
Canonical SMILESO=P(OC1=C(C(C)(C)C)C=C(C(C)(C)C)C=C1)(OC2=C(C(C)(C)C)C=C(C(C)(C)C)C=C2)OC3=C(C(C)(C)C)C=C(C(C)(C)C)C=C3
分子式C42H63O4P
分子量662.92
溶解度DMSO: 2 mg/mL (3.02 mM)
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Tris(2,4-di-tert-butylphenyl)phosphate is an active compound from the leaves of Vitex negundo L. shows anti-inflammatory activity with evidence of inhibition for secretory Phospholipase A2 (sPLA2) through molecular docking[1].

Tris(2,4-di-tert-butylphenyl)phosphate (TDTBPP; 50 mg/kg and 70 mg/kg) exhibits significant anti-inflammatory activity in carrageenan induced paw odema model[1]. Tris(2,4-di-tert-butylphenyl)phosphate (50 mg/kg and 70 mg/kg) reduces the raw paw odema volume significantly[1].

[1]. Vinuchakkaravarthy T, et al. Active compound from the leaves of Vitex negundo L. shows anti-inflammatory activity with evidence of inhibition for secretory Phospholipase A(2) through molecular docking. Bioinformation. 2011;7(4):199-206.