| Cas No. | 148556-27-8 |
| 化学名 | (PB-7-23-111'1'4)-oxodiperoxy(2-pyridinecarboxylato-κN1,κO2)-vanadate(2-), dipotassium, dihydrate |
| Canonical SMILES | O=C1[O-][V+3]23([N]4=CC=CC=C41)([O-][O-]2)([O-][O-]3)=O.[K+].[K+].O.O |
| 分子式 | C6H4NO7V.2K [2H2O] |
| 分子量 | 367.3 |
| 溶解度 | Soluble in DMSO |
| 储存条件 | Store at -20°C, protect from light |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | bpV(pic) is a bisperoxovanadium (bpV) compound that inhibits several different protein tyrosine phosphatases (PTPs), with selectivity for PTEN (IC50 = 31 nM). It also inhibits the vascular endothelial PTP, PTP-β (IC50 = 12.7 μM), and PTP-1βB (IC50 = 61 μM). bpV(pic) is also known to be an insulin mimetic capable of activating the insulin receptor kinase of cultured hepatoma cells, stimulating lipogenesis in adipocytes, and inhibiting the dephosphorylation of autophosphorylated insulin receptors and epidermal growth factor receptors of rat liver endosomes. |
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