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Methyl brevifolincarboxylate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Methyl brevifolincarboxylate图片
CAS NO:154702-76-8
包装:1mg
市场价:1800元

产品介绍
Methylbrevifolincarboxylate(Brevifolincarboxylicacidmethylester)是一种有效的流感病毒PB2帽结合抑制剂。Methylbrevifolincarboxylate对流感病毒A/PuertoRico/8/34(H1N1)和A/Aichi/2/68(H3N2)具有抑制作用,IC50值分别为27.16μM和33.41μM。具有抗氧化活性。
Cas No.154702-76-8
别名短叶苏木酚酸甲酯
Canonical SMILESO=C(C1CC(C2=C1C3=C(O)C(O)=C(O)C=C3C(O2)=O)=O)OC
分子式C14H10O8
分子量306.22
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Methyl brevifolincarboxylate (Brevifolincarboxylic acid methyl ester) is a potent influenza virus PB2 cap-binding inhibitor. Methyl brevifolincarboxylate exhibits inhibitory activity against influenza virus A/Puerto Rico/8/34 (H1N1) and A/Aichi/2/68 (H3N2) with IC50s of 27.16 μM and 33.41 μM. Anti-oxidant activity[1][2].

Methyl brevifolincarboxylate exhibits significant DPPH radical scavenging activity with an IC50 value of 8.9 μM.

[1]. Wu QY, et al. Chromatographic fingerprint and the simultaneous determination of five bioactive components of geranium carolinianum L. water extract by high performance liquid chromatography. Int J Mol Sci. 2011;12(12):8740-8749. [2]. Fang SH, et al. Anti-oxidant and inflammatory mediator's growth inhibitory effects of compounds isolated from Phyllanthus urinaria. J Ethnopharmacol. 2008;116(2):333-340.