| CAS NO: | 123938-86-3 |
| 包装 | 价格(元) |
| 100mg | 电议 |
| 500mg | 电议 |
Glycolchitosan是一种具有亲水性乙二醇支链的壳聚糖衍生物。Glycolchitosan增强了GlycinemaxHarosoy63W细胞的膜通透性和渗漏。Glycolchitosan是水溶性的，生物相容性和可生物降解的。Glycolchitosan可抑制大肠杆菌，金黄色葡萄球菌和肠炎链球菌的生长，MIC值分别为4μg/mL，32μg/mL和<0.5μg/mL。
| Cas No. | 123938-86-3 |
| 别名 | 乙二醇壳聚糖 |
| Canonical SMILES | N[C@@H]1[C@@H](O)[C@H](O)[C@@H](COCCO)C[C@H]1O[C@@H]2[C@@H](COCCO)C[C@@H](O[C@@H]3[C@@H](COCCO)O[C@@H](O)[C@H](N)[C@H]3O)[C@H](N)[C@H]2O.[n] |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 文献引用 | |
| 产品描述 | Glycol chitosan is a chitosan derivative with hydrophilic ethylene glycol branches. Glycol chitosan enhances membrane permeability and leadkage in Glycine max Harosoy 63W cells. Glycol chitosan is water-soluble, biocompatible and biodegradable[1][2][3]. Glycol chitosan inhibits E. coli, S. aureus and S. enteritidis growths with MIC values of 4 μg/mL, 32 μg/mL and Glycol chitosan derivatives have been successfully applied to deliver antimicrobial agents and anticancer drugs such as chemodrugs, genes, and photosensitizers (PSs), either by physical encapsulation or chemical conjugation. Glycol chitosan can be directly linked with hydrophobic drugs to generate amphiphilic compounds that can also form nanoparticles (NPs) for cell imaging and drug delivery. The use of Glycol chitosan derivatives for cell imaging and drug delivery has several advantages, including superb tumor-homing ability in the case of Glycol chitosan NPs based on enhanced permeability and retention (EPR) effect, low cytotoxicity, ease of chemical modification, great biocompatibility, and biodegradability[1].The hydrophobic modification of Glycol chitosan is already confirmed, such as Glycol chitosan bearing a 5β-cholanic acid moiety and deoxycholic acid-Glycol chitosan, could self-assemble into nanoparticles, acting as a promising vehicle for hydrophobic drugs and genes[2]. References: |
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